Kelly L. McGuire

This study reveals the conformational dynamics of Tom70 through structural and computational analyses, showing how its allosteric network coordinates mitochondrial protein import and is modulated by viral interactions.

This paper presents a streamlined method for (an)aerobic vitrification of oxygen-sensitive proteins using an automated device, enabling high-resolution cryoEM structure determination.

This study models the full-length APOBEC3B structure and finds that NTD-CTD interactions increase active site opening frequency.

The paper determines the structure of human mortalin-GrpEL1 complexes using cryoEM and identifies mechanisms of nucleotide and substrate release in the Hsp70 system.

This paper describes the use of the chameleon device for tuning ice thickness to improve cryoEM grid quality and image quality.