NeuroscienceJournal of Alzheimer s DiseasePeer-reviewed
Staging Alzheimer’s disease in the brain and retina of B6.APP/PS1 mice by transcriptional profiling
Sumana R. Chintapaludi, Asli Uyar, Harriet M. Jackson…·Gareth R. Howell
The paper uses RNA sequencing and GLM to analyze molecular changes in B6.APP/PS1 mice brains and retinas, identifying JAK/STAT pathway activation and suggesting limited translatability of retinal changes to human AD.
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