Author

Sumit Sandhu

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Neil HunteriD· 3 shared Yan YuniD· 3 shared H. B. D. Prasada RaoiD· 2 shared Huanyu QiaoiD· 2 shared Addy ThamiD· 1 shared Ajay SharmaiD· 1 shared Amy Shiu LeeiD· 1 shared Anusha Deshpande· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersGenetics

Neil HunterORCID

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3 papers

Recent·Most cited

SUMO mediates the coordinate regulation of meiotic chromosome length and crossover rate

Yan Yun, Huanyu Qiao, Martin A. White, Sumit Sandhu, Wendy Qiu, Sarah L. Bourne, Anusha Deshpande, Shubhang Bhatt, Ajay Sharma, Logan R.J. Bailey, Hung Tran, B. Truong Van, H. B. D. Prasada Rao, Neil Hunter

This study shows SUMO regulates meiotic chromosome length and crossover rate in mice by affecting chromatin loop and axis organization.

bioRxiv · Mar 11, 2026 · PreprintCell Biology

Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis

Masaru Ito, Yan Yun, Dhananjaya S. Kulkarni, Sun‐Kyung Lee, Sumit Sandhu, Briana Nuñez, Lin-Ya Hu, Kevin C. Lee, Nelly Lim, Rachel M. Hirota, Rowan Prendergast, Cynthia Huang, Ivy Huang, Neil Hunter

The paper investigates the distinct and interdependent roles of three RING proteins in regulating meiotic recombination in mice, revealing their unique spatiotemporal dynamics and functional relationships.

Proceedings of the National Academy of Sciences · Jan 6, 2025Peer-reviewedGenetics

Impeding DNA Break Repair Enables Oocyte Quality Control

Huanyu Qiao, H. B. D. Prasada Rao, Yan Yun, Sumit Sandhu, Jared H. Fong, Manali Sapre, Michael Nguyen, Addy Tham, Benjamin W. Van, Tiffany Y.H. Chng, Amy Shiu Lee, Neil Hunter

This study shows RNF212 mediates oocyte quality control by impeding DNA break repair during meiosis, ensuring defective eggs are eliminated.

Molecular Cell · Sep 27, 2018Peer-reviewedGenetics