SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration
Surya Chandra Rao Thumu, Monika Jain, Sumitha Soman, Soumen Das, Vijaya Verma, Arnab Nandi, David H. Gutmann, J. Balaji, Deepak Kumar Nair, James Premdoss Clement, Swananda V. Marathe, Narendrakumar Ramanan
This study shows that deleting SRF in astrocytes creates neuroprotective astrocytes that reduce neuronal damage in mouse models of excitotoxicity and neurodegenerative diseases.
eLife · Jan 30, 2024Peer-reviewedNeuroscience