Swananda V. Marathe

Noradrenergic Depletion by DSP-4 Reduces Morphological Complexity of Hippocampal Astrocytes

This study shows that noradrenergic depletion reduces astrocyte morphological complexity in the hippocampus, but β-adrenergic activation does not restore it, suggesting distinct roles for adrenergic signaling in astrocyte structure and density.

SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

This study shows that deleting SRF in astrocytes creates neuroprotective astrocytes that reduce neuronal damage in mouse models of excitotoxicity and neurodegenerative diseases.

Hippocampal astroglial hypertrophy in mice subjected to early life maternal deprivation

This study shows that maternal deprivation in early life leads to astrocyte hypertrophy in the hippocampus of mice as late as 8 months of age.

Revealing Notch-dependencies in synaptic targets associated with Alzheimer's disease

The paper investigates Notch signaling's role in synaptic dysfunction and Alzheimer's disease by analyzing gene expression in mouse models and human brain tissue, identifying key targets and their expression patterns across disease stages.

Automated Morphometric Analysis Reveals Plasticity Induced by Chronic Antidepressant Treatment in Hippocampal Astrocytes

The paper introduces SMorph, a tool for automated morphometric analysis of nervous system cells, revealing structural remodeling in hippocampal astrocytes after chronic antidepressant treatment.

Subfield-specific Effects of Chronic Mild Unpredictable Stress on Hippocampal Astrocytes

This study examines how chronic mild unpredictable stress affects astrocyte density and morphology in different hippocampal subfields in mice, finding differential effects across subpopulations.