PhysiologyMolecular MetabolismPeer-reviewed
Conditional deletion of CEACAM1 causes hepatic stellate cell activation
Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla…·Sonia Michael Najjar
This study shows that CEACAM1 loss in hepatic stellate cells (HSCs) activates them, leading to myofibroblastic transformation and fibrosis without insulin resistance or steatosis.
18 citations