Sonia Michael Najjar

This study shows that loss of CEACAM2 in mice impairs renal insulin clearance, leading to hyperinsulinemia, insulin resistance, and kidney dysfunction.

This study shows that ablating the Atp1b4 gene in mice reduces obesity and improves metabolic parameters by disrupting evolutionarily acquired BetaM functions.

This study shows that CEACAM1 loss in hepatic stellate cells (HSCs) activates them, leading to myofibroblastic transformation and fibrosis without insulin resistance or steatosis.