AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia
Luting Poh, David Yang‐Wei Fann, Peiyan Wong, Hong Meng Lim, Sok Lin Foo, Sung-Wook Kang, Vismitha Rajeev, Sharmelee Selvaraji, Vinaya Rajagopal Iyer, Nageiswari Parathy, Mohammad Badruzzaman Khan, David Charles Hess, Dong‐Gyu Jo, Grant Raymond Drummond, Christopher Graeme Sobey, , Thiruma Valavan Arumugam
This study shows that AIM2 inflammasome activation contributes to brain injury and cognitive impairment in a mouse model of vascular dementia.
Molecular Psychiatry · Dec 9, 2020Peer-reviewedNeuroscience