Epithelial tubule interconnection driven by HGF-Met signaling in the kidney
Isabel A. López-García, Sunhee Oh, Christopher P. Chaney, Jun Tsunezumi, Iain A. S. Drummond, Leif H. Oxburgh, Thomas J. Carroll, Denise K. Marciano
This study identifies HGF as a key inducer of epithelial tubule anastomosis in vitro and in embryonic kidneys, revealing a proliferation-independent mechanism involving MAPK and MMPs.
Proceedings of the National Academy of Sciences · Dec 20, 2024Peer-reviewedDevelopmental Biology