Denise K. Marciano

This study integrates spatial and single-nucleus transcriptomics to create a gene expression atlas of developing mouse kidneys, revealing heterogeneity in pericytes and introducing the KSTAT tool for analysis.

This study develops an ETP-specific knockout mouse model to demonstrate ETP's critical role in kidney fibrosis during ischemia-reperfusion injury.

This study identifies nine endothelial cell types in the developing murine kidney using snucRNA-Seq and validates novel biomarkers through RNAScope.

This study identifies the roles of canonical and non-canonical Wnt signaling pathways in directing epithelial tubule interconnection during zebrafish kidney regeneration.

This study identifies HGF as a key inducer of epithelial tubule anastomosis in vitro and in embryonic kidneys, revealing a proliferation-independent mechanism involving MAPK and MMPs.

This study shows Rab11 is essential for pancreas development, lumen formation, and endocrine mass by regulating epithelial morphogenesis and vesicle trafficking.

The paper identifies novel truncating mutations in CTNND1 associated with craniofacial and cardiac anomalies, expanding the known phenotypic spectrum of the gene.