ImmunologybioRxivPreprint
Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-kB
Nadja Lucas, Sophia Weidler, Antonia Eicher…·Min Ae Lee‐Kirsch
This study identifies truncating RELA variants causing autoinflammation and autoimmunity by disrupting NF-κB feedback control and immune homeostasis.
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