Christine Wolf

The paper identifies how 3-mer oligonucleotides with base and sugar modifications modulate TLR7 and TLR8 responses, leading to the development of a dual inhibitory oligonucleotide for autoimmune disease.

This study identifies truncating RELA variants causing autoinflammation and autoimmunity by disrupting NF-κB feedback control and immune homeostasis.

This paper introduces a FACS-based preprocessing workflow for PBMCs that improves scRNA-seq throughput and preserves biological integrity while enabling rare cell enrichment and cross-donor multiplexing.