Predicted Bacterial uRBSs Reveal Translational Coupling and Ribosome Mediated RBS Occlusion as Gene-Controlling Mechanisms
Theresa Dietz, Julian M. Hahnfeld, Sophie Neumann, Yonca A. Reinsch, Tessa Wenz, Susanne Barth-Weber, Jochen Blom, Alexander Goesmann, Elena Evguenieva‐Hackenberg
The paper identifies uORFs in bacterial mRNAs using bioinformatics and experimental validation, revealing translational coupling and ribosome-mediated RBS occlusion as regulatory mechanisms.
microLife · Jan 1, 2026Peer-reviewedMolecular Biology