Rampant transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of a human fungal pathogen
S. J. Priest, V. Yadav, C. Roth, T. A. Dahlmann, U. Kuck, P. M. Magwene, J. Heitman
The paper identifies hypermutation and antifungal drug resistance in Cryptococcus neoformans clinical isolates caused by RNAi loss and transposon proliferation.
bioRxiv · Aug 11, 2021Microbiology