V. Yadav

A Mem-dELISA platform for dual color and ultrasensitive digital detection of colocalized proteins on extracellular vesicles

The paper introduces a Mem-dELISA platform for ultrasensitive, dual-color detection of colocalized proteins on extracellular vesicles, demonstrating its application in cancer research.

Discovery of Mycodnaviridae, a clade of giant viruses that persistently infect zoosporic fungi

The paper discovers a new family of giant viruses, Mycodnaviridae, that infect zoosporic fungi and persistently infect them, expanding the known host range of Nucleocytoviricota.

A mitochondrial quality control mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis

This study identifies a mitochondrial quality control mechanism that reverses phagosome maturation arrest caused by Mycobacterium tuberculosis through RAB7 recruitment and lysosomal targeting.

SIRT1 and SIRT3 impact host mitochondrial function and host- Salmonella pH balance during infection

This study shows that SIRT1 and SIRT3 regulate mitochondrial function and pH balance in macrophages during Salmonella infection, affecting bacterial gene expression.

Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India

This study evaluates a new live-attenuated LSD vaccine, showing it is safe, immunogenic, and effective in protecting cattle against LSD with high seroconversion rates.

Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans

The paper investigates heat stress-induced transposon mobility in Cryptococcus deneoformans using whole-genome sequencing, finding increased retroelement mobilization at 37°C compared to 30°C.

Moxifloxacin-mediated killing of Mycobacterium tuberculosis involves respiratory downshift, reductive stress, and ROS accumulation

This study identifies moxifloxacin-induced oxidative stress in Mycobacterium tuberculosis as a mechanism of killing, showing that reductive stress and iron contribute to ROS accumulation and drug efficacy.

Rampant transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of a human fungal pathogen

The paper identifies hypermutation and antifungal drug resistance in Cryptococcus neoformans clinical isolates caused by RNAi loss and transposon proliferation.

Spatiotemporal sensitivity of embryonic heart specification to FGFR signaling in Drosophila

This study uses an optogenetic tool to show that Drosophila embryos are most sensitive to Htl over-activation during a specific developmental window, affecting heart morphogenesis.

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans

This study identifies cell cycle regulators involved in ploidy transitions during unisexual reproduction in C. deneoformans and reveals segmental aneuploidy associated with azole resistance.

Rare genera differentiate urban green space soil bacterial communities in three cities across the world

The paper examines the relationship between vegetation complexity and soil bacterial communities in urban green spaces across three cities, finding that rare genera significantly differ between vegetation complexity categories.

Uniparental nuclear inheritance following bisexual mating in fungi

The paper discovers pseudosexual reproduction in Cryptococcus neoformans, where only one parental nucleus is inherited during bisexual mating, similar to hybridogenesis in animals.

Tissue pressure and cell traction compensate to drive robust aggregate spreading

This study shows cell aggregates adjust their spreading dynamics on different substrates by compensating between tissue pressure and cell traction forces.

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

This paper identifies centromeres in Phytophthora sojae using long-read sequencing and ChIP-seq, revealing transposon-rich, heterochromatic regions distinct from other SAR supergroup organisms.