Recruitment of Two Dyneins to an mRNA-Dependent Bicaudal D Transport Complex
T. E. Sladewski, N. Billington, M. Y. Ali, C. S. Bookwalter, H. Lu, E. B. Krementsova, T. A. Schroer, K. M. Trybus
The paper shows that full-length BicD requires both Egl and mRNA to activate dynein-dynactin motility for mRNA transport, recruiting two dyneins to enhance transport efficiency.
bioRxiv · Feb 28, 2018Biophysics