Author

M. Y. Ali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:Drosophila· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

K. M. Trybus· 4 shared E. B. Krementsova· 2 shared H. Cui· 2 shared S. R. Solmaz· 2 shared C. S. Bookwalter· 1 shared C. Wang· 1 shared E. W. Debler· 1 shared H. Lu· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBiophysics

K. M. Trybus

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4 papers

Recent·Most cited

Coil-to-Helix Transition at the Nup358-BicD2 Interface Activates BicD2 for Dynein Recruitment

J. M. Gibson, H. Cui, M. Y. Ali, X. Zhao, E. W. Debler, J. Zhao, K. M. Trybus, S. R. Solmaz, C. Wang

The paper identifies a Nup358 helix that transitions to an α-helix upon BicD2 binding, facilitating dynein recruitment and processive motility.

bioRxiv · May 6, 2021Biophysics

Coiled-coil registry shifts in the F684I mutant of Bicaudal result in cargo-independent activation of dynein motility

H. Cui, K. M. Trybus, M. Y. Ali, P. Goyal, K. Zhang, J. Y. Loh, S. R. Solmaz

The paper shows that a coiled-coil registry shift in the F684I mutant of BicD activates dynein motility without cargo, and suggests this mechanism may modulate cargo selection in BicD2.

bioRxiv · Nov 29, 2019Biophysics

Recruitment of Two Dyneins to an mRNA-Dependent Bicaudal D Transport Complex

T. E. Sladewski, N. Billington, M. Y. Ali, C. S. Bookwalter, H. Lu, E. B. Krementsova, T. A. Schroer, K. M. Trybus

The paper shows that full-length BicD requires both Egl and mRNA to activate dynein-dynactin motility for mRNA transport, recruiting two dyneins to enhance transport efficiency.

bioRxiv · Feb 28, 2018Biophysics

Small teams of myosin Vc coordinate their stepping for efficient cargo transport on actin bundles

E. B. Krementsova, K. Furuta, K. Oiwa, K. M. Trybus, M. Y. Ali

This study compares the stepping behavior of myosin Vc teams and myosin Va, showing that myoVc teams move more efficiently on actin bundles due to coordinated stepping.

bioRxiv · Mar 18, 2017Biophysics