The systemic activin response to pancreatic cancer: Implications for effective cancer cachexia therapy
X. Zhong, M. Pons, C. Poirier, Y. Jiang, J. Liu, G. E. Sandusky, Y. Liu, G. Jiang, M. Couch, L. G. Koniaris, T. A. Zimmers
This study shows that pancreatic cancer induces a systemic activin response contributing to cachexia, and that targeting both tumor and host-derived activins may improve therapy.
bioRxiv · Jun 11, 2018Cancer Biology