Developmental BiologyScience AdvancesPeer-reviewed
CTCF, BEAF-32 and CP190 are not required for the initial establishment of TADs in early Drosophila embryos, but have locus specific roles
Gabriel R. Cavalheiro, Charles Girardot, Rebecca R. Viales…·Eileen E. M. Furlong
The paper shows TADs form during zygotic genome activation in Drosophila embryos without CTCF, BEAF-32, or CP190, but these factors have locus-specific roles in boundary insulation.
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