Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth
K. Shah, R. H. Whitaker, T. Busby, J. Hu, B. Shi, Z. Wang, C. Zang, W. J. Placzek, H. Jiang
The paper develops DPY30-targeting peptides that inhibit blood cancer cell growth by disrupting ASH2L binding and H3K4 methylation.
bioRxiv · Feb 19, 2019Cancer Biology