Author

T. Busche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 4 Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Organism:plant (other)· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

J. Kalinowski· 5 shared A. Koch· 3 shared A. Lopez-Rodriguez· 2 shared A. Moebus· 2 shared C. Preusser· 2 shared D. Biedenkopf· 2 shared F. Brasch· 2 shared F. Oppel· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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5 shared papersMicrobiology

J. Kalinowski

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Author profile →

8 papers

Recent·Most cited

HPV-positive head and neck squamous cell carcinoma cells lose viability during triggered myocyte lineage differentiation

S. Gendreizig, L. Martinez-Ruiz, A. Lopez-Rodriguez, H. Pabla, L. Hose, F. Brasch, T. Busche, G. Escames, H. Sudhoff, L. U. Scholtz, I. Todt, F. Oppel

This study shows HPV+ HNSCC cells lose viability during myocyte-like differentiation in vitro, with upregulated myofibril markers and potential therapeutic implications.

bioRxiv · Mar 28, 2024 · PreprintCancer Biology

Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase

C. Schmerling, C. Schroeder, X. Zhou, T. Busche, J. Kalinowski, L. Montero, O. Schmitz, F. Kaschani, S. Ninck, M. Kaiser, J. Bost, B. Wassmer, S.-V. Albers, B. Siebers, C. Braesen

This study identifies an unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius involved in glycerol degradation, showing its essential role in growth on glycerol.

bioRxiv · Feb 29, 2024 · PreprintMicrobiology

Inducible mucosa-like differentiation of head and neck cancer cells drives the epigenetically determined loss of cell malignancy

F. Oppel, S. Gendreizig, L. Martinez-Ruiz, J. Florido, A. Lopez-Rodriguez, H. Pabla, L. Loganathan, L. Hose, P. Kuehnel, P. Schmidt, M. Schuermann, J. M. Neumann, F. Viyof Ful, L. U. Scholtz, D. Ligum, , H. Sudhoff

This study shows that HNSCC cells can differentiate into non-malignant cells, losing their tumor-initiating potential and expressing KRT17, suggesting differentiation as a therapeutic target.

bioRxiv · Jun 30, 2023 · PreprintCancer Biology

Uncoupling of the Diurnal Growth Program by Artificial Genome Relaxation in Synechocystis sp. PCC 6803

A. Behle, M. Dietsch, L. Goldschmidt, W. Murugathas, D. Brandt, T. Busche, J. Kalinowski, O. Ebenhoeh, I. M. Axmann, R. Machne

The paper manipulates DNA supercoiling in Synechocystis sp. PCC 6803 using CRISPRi and TopoI overexpression, revealing its role in diurnal gene regulation and growth.

bioRxiv · Jul 26, 2021 · PreprintMicrobiology

Isolation and characterization of barley (Hordeum vulgare) extracellular vesicles and their role in RNAi-based crop protection

T. Schlemmer, L. Weipert, C. Preusser, M. Hardt, A. Moebus, P. Barth, T. Busche, A. Koch

This study isolates and characterizes barley extracellular vesicles and shows they contain siRNAs but play a minor role in spray-induced gene silencing compared to HIGS.

bioRxiv · Apr 26, 2021Plant Biology

Host-induced gene silencing involves Arabidopsis ESCRT-III pathway for the transfer of dsRNA-derived siRNA

T. Schlemmer, L. Weipert, P. Barth, B. Werner, C. Preusser, M. Hardt, A. Moebus, D. Biedenkopf, M. Claar, L. Jelonek, A. Goesmann, V. Garikapati, B. Spengler, T. Busche, J. Kalinowski, A. Koch

This study identifies the Arabidopsis ESCRT-III pathway as essential for transferring dsRNA-derived siRNAs between host and fungal cells during host-induced gene silencing.

bioRxiv · Feb 12, 2020 · PreprintPlant Biology

Phloem-mediated spreading of SIGS-derived non-coding RNAs in Hordeum vulgare

D. Biedenkopf, T. Will, T. Knauer, L. Jelonek, A. C. U. Furch, T. Busche, A. Koch

This study investigates the phloem-mediated spread of SIGS-derived non-coding RNAs in barley, showing their systemic translocation and uptake by pathogens/pests.

bioRxiv · Dec 30, 2019 · PreprintPlant Biology

Discovery of interaction-related sRNAs and their targets in the Brachypodium distachyon and Magnaporthe oryzae pathosystem

S. Zanini, E. Secic, T. Busche, J. Kalinowski, K.-H. Kogel

This study identifies bidirectional small RNA (sRNA) effectors and their targets between the rice blast fungus Magnaporthe oryzae and the grass Brachypodium distachyon, providing experimental evidence for cross-kingdom RNA interference (ckRNAi).

bioRxiv · May 24, 2019Plant Biology