Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology
A. Sontheimer-Phelps, D. B. Chou, A. Tovaglieri, T. C. Ferrante, T. Duckworth, C. Fadel, V. Frismantas, S. Jalili Firoozinezhad, M. Kasendra, E. Stas, J. C. Weaver, C. A. Richmond, O. Levy, R. Prantil-Baun, D. T. Breault, D. E. Ingber
This study develops a human colon-on-a-chip model that replicates the mucus bilayer structure and function, enabling real-time non-invasive analysis of mucus layer dynamics.
bioRxiv · Aug 20, 2019Cell Biology