Author

T. C. Freeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. S. Tavares· 1 shared A. M. Fraser· 1 shared A. N. Akbar· 1 shared A. Patir· 1 shared B. B. Shih· 1 shared C. Farquharson· 1 shared C. J. Alcaide-Corral· 1 shared D. Gilroy· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

A. A. S. Tavares

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Author profile →

3 papers

Recent·Most cited

A systems-level analysis of dynamic total-body PET data reveals complex skeletal energy metabolism networks in vivo

K. J. Suchacki, C. J. Alcaide-Corral, S. Nimale, M. G. Macaskill, R. H. Stimson, C. Farquharson, T. C. Freeman, A. A. S. Tavares

The paper uses total-body PET scans to analyze dynamic skeletal energy metabolism networks in mice, revealing unique glucose metabolism patterns across bones and their complex interactions.

bioRxiv · Feb 16, 2021Physiology

Monocyte-derived Prostaglandin E2 inhibits antigen-specific cutaneous immunity during ageing

E. S. Chambers, M. Vukmanovic-Stejic, B. B. Shih, H. Trahir, P. Subramanian, O. P. Devine, J. Glanville, D. Gilroy, M. Rustin, T. C. Freeman, N. A. Mabbott, A. N. Akbar

This study shows that inflammation from tissue injury in older adults reduces cutaneous immunity to VZV by recruiting monocytes that produce PGE2, which can be reversed with a p38-MAPK inhibitor.

bioRxiv · Apr 2, 2020Immunology

The transcriptional signature associated with human motile cilia

A. Patir, A. M. Fraser, M. W. Barnett, L. McTeir, J. Rainger, M. G. Davey, T. C. Freeman

This paper identifies a transcriptional signature of 248 genes associated with human motile cilia, validated through multiple approaches including literature review, databases, and localization experiments.

bioRxiv · Oct 24, 2019Cell Biology