Author

T. C. M. Seegar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

S. C. Blacklow· 2 shared A. Kruse· 1 shared G. Adelmant· 1 shared J. A. Marto· 1 shared J. C. Aster· 1 shared K. J. Susa· 1 shared M. Andrews· 1 shared S. M. Jarrett· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

S. C. Blacklow

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2 papers

Recent·Most cited

ImmunologybioRxivSep 13, 2019

A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

K. J. Susa, T. C. M. Seegar, S. C. Blacklow, A. Kruse

This study shows that CD81 controls CD19 trafficking to the cell surface through a dynamic interaction, with implications for B cell function and tetraspanin biology.

DOI 10.7554/elife.52337

humanexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 23, 2019

Molecular basis for feedback inhibition of Notch signaling by the Notch regulated ankyrin repeat protein NRARP

S. M. Jarrett, T. C. M. Seegar, M. Andrews…·S. C. Blacklow

This study identifies the molecular mechanism by which NRARP inhibits Notch signaling by binding to the NTC complex and disrupting its function.

DOI 10.1101/645937

humanproteomics

𝕏 PostBluesky