Author

T. H. Hwang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 5 Organism:human· 5 Approach:deep learning· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2

Frequent Co-Authors

C. Hong· 4 shared J. Lathia· 2 shared A. C. Yopp· 1 shared A. J. Lauko· 1 shared A. Lo· 1 shared A. M. Khalil· 1 shared B. Dropulic· 1 shared B. Otvos· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersImmunology

C. Hong

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Revealing 3D cancer tissue structures using holotomography and virtual hematoxylin and eosin staining via deep learning

J. park, S.-J. Shin, M. Kim, g. kim, H. cho, d. ryu, d. ahn, j. e. heo, h.-s. min, K. S. Lee, Y. Park, T. H. Hwang

This paper develops a 3D virtual H&E staining method using holotomography and deep learning for cancer tissues, validated on colon and gastric cancer samples.

bioRxiv · Dec 4, 2023 · PreprintCancer Biology

Integrative Spatial Analysis of H&E and IHC Images Identifies Prognostic Immune Subtypes Correlated with Progression-Free Survival in HPV-Related Oropharyngeal Squamous Cell Carcinoma

S. R. Nakkireddy, I. Jang, M. Rivera, J. J. Garcia, K. R. Bartemes, D. M. Routman, D. J. Ma, K. M. Van Abel, T. H. Hwang

The paper integrates H&E and IHC images to identify immune subtypes in HPV-related oropharyngeal cancer, finding that immune inflamed subtypes correlate with better progression-free survival.

bioRxiv · Sep 13, 2023 · PreprintCancer Biology

Sequential single cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin lymphoma

Z. G. Jackson, C. Hong, R. Schauner, B. Dropulic, P. F. Caimi, M. de Lima, K. Gupta, J. S. Reese, T. H. Hwang, D. N. Wald

The paper identifies TIGIT as a marker of CD19 CAR-T cell dysfunction in NHL patients through single-cell transcriptional and protein profiling.

bioRxiv · Apr 26, 2021Immunology

Single-Cell Analysis of Hyperthermic Intraperitoneal Chemotherapy Treated Tumors Reveals Distinct Cellular and Molecular Responses

M. P. Horowitz, Z. Alali, T. Alban, C. Hong, E. Esakov, T. H. Hwang, J. Lathia, C. M. Michener, R. DeBernardo, O. Reizes

This study uses single-cell RNA-seq to analyze tumor responses to HIPEC in ovarian cancer patients, identifying distinct cellular and molecular changes.

bioRxiv · Oct 5, 2020 · PreprintCancer Biology

Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner

D. Bayik, Y. Zhou, C. Park, C. Hong, D. Vail, D. J. Silver, A. J. Lauko, G. A. Roversi, D. C. Watson, A. Lo, T. J. Alban, M. McGraw, M. D. Sorensen, M. M. Grabowski, B. Otvos, , J. Lathia

This study identifies sex-specific roles of MDSC subsets in glioblastoma, showing mMDSCs drive growth in males and gMDSCs in females, with potential therapeutic targets.

bioRxiv · Feb 19, 2020Immunology

Hispanic/Latino gastric adenocarcinoma patients have distinct molecular profiles including a high rate of germline CDH1 mutations

S. C. Wang, Y. Yeu, S. T. Hammer, S. Xiao, M. Zhu, C. Hong, L. Y. Yoon, I. Nassour, J. Shen, D. Agarwal, S. I. Reznik, J. C. Mansour, A. C. Yopp, H. Zhu, T. H. Hwang, M. R. Porembka

This study identifies distinct molecular profiles in Hispanic/Latino gastric cancer patients, including a high rate of CDH1 germline mutations linked to aggressive clinical outcomes.

bioRxiv · Sep 11, 2019Cancer Biology