Author

G. A. Roversi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. J. Silver· 3 shared A. Lo· 2 shared D. Bayik· 2 shared J. D. Lathia· 2 shared J. M. Brown· 2 shared A. J. Lauko· 1 shared A. Lauko· 1 shared A. M. Khalil· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

D. J. Silver

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma

D. J. Silver, G. A. Roversi, N. Bithi, C. K. A. Neumann, K. M. Troike, G. K. Ahuja, O. Reizes, J. M. Brown, C. Hine, J. D. Lathia

A high-fat diet accelerates glioblastoma by inhibiting hydrogen sulfide production, leading to cancer stem cell enrichment and reduced treatment response.

bioRxiv · Mar 8, 2020 · PreprintCancer Biology

Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner

D. Bayik, Y. Zhou, C. Park, C. Hong, D. Vail, D. J. Silver, A. J. Lauko, G. A. Roversi, D. C. Watson, A. Lo, T. J. Alban, M. McGraw, M. D. Sorensen, M. M. Grabowski, B. Otvos, , J. Lathia

This study identifies sex-specific roles of MDSC subsets in glioblastoma, showing mMDSCs drive growth in males and gMDSCs in females, with potential therapeutic targets.

bioRxiv · Feb 19, 2020Immunology

Cholangiocarcinoma presents a distinct myeloid-derived suppressor cell signature compared to other hepatobiliary cancers

D. Bayik, A. Lauko, G. A. Roversi, E. Serbinowski, L.-A. Acevedo-Moreno, C. Lanigan, M. Orujov, A. Lo, T. Alban, D. J. Silver, J. M. Brown, D. S. Allende, F. N. Aucejo, J. D. Lathia

The paper identifies a distinct myeloid-derived suppressor cell (MDSC) signature in cholangiocarcinoma (CCA) compared to other hepatobiliary cancers, linking MDSC levels to disease outcomes and potential therapeutic targets.

bioRxiv · Dec 11, 2019 · PreprintPathology