Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli
C. Boulouis, W. R. Sia, M. Y. Gulam, J. Q. M. Teo, T. K. Phan, J. Y. W. Mak, D. P. Fairlie, I. K. H. Poon, T. H. Koh, P. Bergman, L.-F. Wang, A. L. H. Kwa, J. K. Sandberg, E. Leeansyah
This study shows human MAIT cells use granulysin and granzyme B to overcome carbapenem resistance in E. coli by increasing bacterial permeability and restoring carbapenem efficacy.
bioRxiv · Jan 16, 2020Immunology