Author

T. K. Phan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

I. K. H. Poon· 2 shared A. K. Coussens· 1 shared A. L. H. Kwa· 1 shared B. Shi· 1 shared C. Boulouis· 1 shared D. C. Ozkocak· 1 shared D. P. Fairlie· 1 shared D. Sheerin· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

I. K. H. Poon

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Voltage-gated T-type calcium channel blockers reduce apoptotic body-mediated SARS-CoV-2 cell-to-cell spread and subsequent cytokine storm

T. K. Phan, D. Sheerin, B. Shi, M. Dayton, L. Mackiewicz, D. C. Ozkocak, G. Atkin-Smith, N. Peton, O. Audi, R. Tixeira, G. Ashdown, K. C. Davidson, M. Doerflinger, A. K. Coussens, I. K. H. Poon

This study shows that T-type calcium channel blockers reduce SARS-CoV-2 spread via apoptotic bodies and limit cytokine storms in macrophages.

bioRxiv · Nov 3, 2023 · PreprintCell Biology

Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli

C. Boulouis, W. R. Sia, M. Y. Gulam, J. Q. M. Teo, T. K. Phan, J. Y. W. Mak, D. P. Fairlie, I. K. H. Poon, T. H. Koh, P. Bergman, L.-F. Wang, A. L. H. Kwa, J. K. Sandberg, E. Leeansyah

This study shows human MAIT cells use granulysin and granzyme B to overcome carbapenem resistance in E. coli by increasing bacterial permeability and restoring carbapenem efficacy.

bioRxiv · Jan 16, 2020Immunology