MicrobiologybioRxiv
An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency
T. Kotaki, T. Kurosu, A. Grinyo…·M. Kameoka
This study identifies an affinity-matured human monoclonal antibody, 3G9, targeting the fusion loop epitope of dengue virus that shows strong neutralization and reduced antibody-dependent enhancement in vivo.
DOI 10.1038/s41598-021-92403-9