Author

T. Haegele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Hausser· 1 shared G. Link· 1 shared J. E. Burke· 1 shared K. Hirzel· 1 shared M. A. H. Parson· 1 shared R. Reinhardt· 1 shared S. A. Eisler· 1 shared T. A. Leonard· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Hausser

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1 paper

Recent·Most cited

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis

R. Reinhardt, K. Hirzel, G. Link, S. A. Eisler, T. Haegele, M. A. H. Parson, J. E. Burke, A. Hausser, T. A. Leonard

This study shows PKD is regulated by trans-autoinhibition followed by cis autophosphorylation, switching the kinase on by preventing re-autoinhibition.

bioRxiv · May 5, 2022Biochemistry