Author

R. Reinhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Assay:ChIP-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Hausser· 1 shared A. Keating· 1 shared A. Migur· 1 shared A. Srikumar· 1 shared B. Huettel· 1 shared B. Liu· 1 shared C. Steglich· 1 shared F. Heyl· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. Hausser

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Author profile →

4 papers

Recent·Most cited

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis

R. Reinhardt, K. Hirzel, G. Link, S. A. Eisler, T. Haegele, M. A. H. Parson, J. E. Burke, A. Hausser, T. A. Leonard

This study shows PKD is regulated by trans-autoinhibition followed by cis autophosphorylation, switching the kinase on by preventing re-autoinhibition.

bioRxiv · May 5, 2022Biochemistry

The temperature-regulated DEAD-box RNA helicase CrhR interactome: Autoregulation and photosynthesis-related transcripts

A. Migur, F. Heyl, J. Fuss, A. Srikumar, B. Huettel, C. Steglich, J. S. S. Prakash, R. Reinhardt, R. Backofen, G. W. Owttrim, W. R. Hess

This study identifies the RNA interactome of the cyanobacterial DEAD-box helicase CrhR, revealing its role in photosynthesis and redox regulation through auto-regulation and binding of photosynthesis-related transcripts.

bioRxiv · Mar 26, 2021Plant Biology

The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1,RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation

M. Kamran, J. Liang, B. Liu, Y. Li, J. Gao, A. Keating, F. Mohamed, S. Dai, R. Reinhardt, Y. Jiong, Z. Wu, H. Huang

This study identifies Il13 enhancers that mediate gene transcription in response to antigenic stimulation by analyzing histone modifications and transcription factor binding sites.

bioRxiv · Sep 29, 2020Immunology

TNFR2 induced priming of NLRP3-inflammasome via RIPK1 leads to pyroptosis in XIAP deficient cells

J. Knop, L. M. Spilgies, S. Rufli, R. Reinhardt, L. Vasilikos, M. Yabal, P. J. Jost, H. Wajant, M. D. Robinson, T. Kaufmann, W. W.-L. Wong

The paper shows TNFR2 activation in XIAP-deficient cells leads to NLRP3 inflammasome priming and pyroptosis via RIPK1 and ROS, with implications for reducing IL-18 release in XLP-2 patients.

bioRxiv · Feb 15, 2019Immunology