Author

S. A. Eisler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Braun· 1 shared A. Hausser· 1 shared A. Lindner· 1 shared B. Noll· 1 shared C. Lungu· 1 shared D. Benz· 1 shared D. Imig· 1 shared D. Stöhr· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Braun

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis

R. Reinhardt, K. Hirzel, G. Link, S. A. Eisler, T. Haegele, M. A. H. Parson, J. E. Burke, A. Hausser, T. A. Leonard

This study shows PKD is regulated by trans-autoinhibition followed by cis autophosphorylation, switching the kinase on by preventing re-autoinhibition.

bioRxiv · May 5, 2022Biochemistry

The GEF-GAP pair Solo and DLC3 balances Rho activity during endocytic transport

C. Lungu, F. Meyer, M. Hörning, J. Steudle, A. Braun, B. Noll, D. Benz, F. Frankle, S. Schmid, S. A. Eisler, M. A. Olayioye

This study identifies Solo and DLC3 as a RhoGAP-RhoGEF pair that regulates RhoB activity and levels during endocytic transport through combined RNAi screening and biochemical assays.

bioRxiv · Mar 1, 2022 · PreprintCell Biology

Cell-to-cell heterogeneities during extrinsic apoptosis arise from cell cycle progression and transmitotic apoptosis resistance

N. Pollak, A. Lindner, D. Imig, K. Kuritz, J. S. Fritze, I. Heinrich, J. Stadager, S. A. Eisler, D. Stöhr, F. Allgöwer, P. Scheurich, M. Morrison (Rehm)

The paper shows that cell cycle phase affects apoptosis resistance and outcomes in isogenic cells during extrinsic apoptosis.

bioRxiv · Feb 26, 2021 · PreprintCell Biology