Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism
M.-L. Lee, H. Matsunaga, Y. Sugiura, T. Hayasaka, I. Yamamoto, D. Imoto, M. Suematsu, N. Iijima, K. Kimura, S. Diano, C. Toda
This study shows that cPLA2-mediated phospholipid metabolism in the VMH regulates glucose metabolism under RCD but worsens it under HFD through changes in insulin sensitivity and inflammation.
bioRxiv · May 18, 2020Physiology