Author

M. Suematsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:metabolism & bioenergetics· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

Y. Sugiura· 4 shared H. Kobayashi· 2 shared K. Takubo· 2 shared M. Yamamoto· 2 shared S. Watanuki· 2 shared T. Morikawa· 2 shared A. Iwama· 1 shared A. Nakamura-Ishizu· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersCell Biology

Y. Sugiura

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

S. Watanuki, H. Kobayashi, Y. Sugiura, M. Yamamoto, D. Karigane, K. Shiroshita, Y. Sorimachi, S. Fujita, T. Morikawa, S. Koide, M. Oshima, A. Nishiyama, K. Murakami, H. Miho, S. Tamaki, , K. Takubo

This study identifies PFKFB3 as a key regulator of glycolytic metabolism in HSCs under stress, showing its context-dependent activation promotes ATP production and hematopoiesis.

bioRxiv · Mar 16, 2023Cell Biology

The CWI pathway is activated through high hydrostatic pressure, enhancing glycerol efflux via the aquaglyceroporin Fps1 in Saccharomyces cerevisiae

T. Mochizuki, T. Tanigawa, S. Shindo, M. Suematsu, Y. Oguchi, T. Mioka, Y. Kato, M. Fujiyama, E. Hatano, M. Yamaguchi, H. Chibana, F. Abe

This study shows high hydrostatic pressure activates the CWI pathway in yeast, leading to increased glycerol efflux via Fps1 to counteract osmotic stress.

bioRxiv · Nov 15, 2022 · PreprintCell Biology

Senescent cell death as an aging resistance mechanism in naked mole-rat

Y. Kawamura, K. Oka, M. Takamori, Y. Sugiura, Y. Oiwa, S. Fujioka, S. Homma, S. Miyawaki, M. Narita, T. Fukuda, M. Suematsu, H. Bono, H. Okano, K. Miura

This study identifies senescent cell death as a mechanism contributing to the aging resistance in naked mole-rats, linking low antioxidant defense with suppressed senescent cell accumulation.

bioRxiv · Jul 2, 2020Cell Biology

Visualizing ATP Dynamics in Live Mice

N. Koitabashi, R. Ogasawara, R. Yasui, Y. Sugiura, H. Matsuda, S. Nonaka, T. Izumi, M. Kurabayashi, M. Suematsu, M. Yanagita, H. Imamura, M. Yamamoto

The paper develops a transgenic mouse model with GO-ATeam to measure ATP dynamics in real-time across multiple organs and conditions, providing insights into ATP's role in physiology and disease.

bioRxiv · Jun 10, 2020 · PreprintPhysiology

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism

M.-L. Lee, H. Matsunaga, Y. Sugiura, T. Hayasaka, I. Yamamoto, D. Imoto, M. Suematsu, N. Iijima, K. Kimura, S. Diano, C. Toda

This study shows that cPLA2-mediated phospholipid metabolism in the VMH regulates glucose metabolism under RCD but worsens it under HFD through changes in insulin sensitivity and inflammation.

bioRxiv · May 18, 2020Physiology

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

H. Kobayashi, T. Morikawa, A. Okinaga, F. Hamano, T. Hashidate-Yoshida, S. Watanuki, D. Hishikawa, H. Shindou, F. Arai, Y. Kabe, M. Suematsu, T. Shimizu, K. Takubo

This study maintains engraftable quiescent HSCs in culture for 1 month using low cytokines, hypoxia, and high fatty acids.

bioRxiv · Dec 6, 2018Cell Biology