Author

M.-L. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Toda· 3 shared D. Imoto· 2 shared H. Matsunaga· 2 shared I. Yamamoto· 2 shared K. Kimura· 2 shared N. Iijima· 2 shared C.-P. Chang· 1 shared K. X. KATO· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPhysiology

C. Toda

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3 papers

Recent·Most cited

Body temperature regulates glucose metabolism and torpid

M.-l. Lee, C.-P. Chang, C. Toda, T. Nemoto, R. Enoki

This study shows that body temperature, not ambient temperature, strongly regulates glucose metabolism and behavior in QIH mice, with hypometabolism being secondary to hypothermia.

Nature Communications · Jul 10, 2025Peer-reviewedPhysiology

Activation of prodynorphin neurons in the dorsomedial hypothalamus inhibits food intake and promotes positive valence

D. Imoto, I. Yamamoto, H. Matsunaga, T. Yonekura, M.-L. Lee, K. X. KATO, T. Yamasaki, K.-i. Otsuguro, M. Horiuchi, N. Iijima, K. Kimura, C. Toda

The paper identifies refeeding-responsive neurons in the dorsomedial hypothalamus that reduce food intake and enhance positive valence when activated.

bioRxiv · Jul 2, 2020 · PreprintPhysiology

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism

M.-L. Lee, H. Matsunaga, Y. Sugiura, T. Hayasaka, I. Yamamoto, D. Imoto, M. Suematsu, N. Iijima, K. Kimura, S. Diano, C. Toda

This study shows that cPLA2-mediated phospholipid metabolism in the VMH regulates glucose metabolism under RCD but worsens it under HFD through changes in insulin sensitivity and inflammation.

bioRxiv · May 18, 2020Physiology