Author

T. Hessler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

J. F. Banfield· 2 shared R. J. Huddy· 2 shared S. T. L. Harrison· 2 shared A. Boltengagen· 1 shared A. Oliveras Martinez· 1 shared A. Rybak-Wolf· 1 shared A. Woehler· 1 shared A. Zappulo· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

J. F. Banfield

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Vitamin interdependencies predicted by metagenomics-informed network analyses validated in microbial community microcosms

T. Hessler, R. J. Huddy, R. Sachdeva, S. Lei, S. T. L. Harrison, S. Diamond, J. F. Banfield

The paper predicts vitamin interdependencies in microbial communities using metagenomics-informed network analysis and validates these predictions in microcosms.

bioRxiv · Jan 27, 2023Microbiology

RNA-targeting CRISPR-Cas13 Provides Broad-spectrum Phage Immunity

B. A. Adler, T. Hessler, B. F. Cress, V. K. Mutalik, R. K. Barrangou, J. Banfield, J. A. Doudna

This paper demonstrates that LbuCas13a can broadly inhibit diverse E. coli phages and enable efficient, markerless phage genome editing.

bioRxiv · Mar 25, 2022 · PreprintMicrobiology

Spatio-temporal, optogenetic control of gene expression in organoids

I. Legnini, L. Emmenegger, A. Zappulo, R. Wurmus, A. Oliveras Martinez, C. Cerda Jara, A. Boltengagen, T. Hessler, G. Mastrobuoni, A. Rybak-Wolf, S. Kempa, R. P. Zinzen, A. Woehler, N. Rajewsky

This study uses optogenetic control to manipulate gene expression in organoids, demonstrating its ability to generate patterned tissue structures and reveal new insights into neurodevelopmental gene regulation.

bioRxiv · Sep 26, 2021 · PreprintBioengineering

Syntrophic H2 production enhances the performance of primarily acetate-supplemented reactors treating sulphate contaminated solutions

T. Hessler, S. T. L. Harrison, J. F. Banfield, R. J. Huddy

This study shows that adding a small amount of fermentable substrate to acetate-supplemented sulfate-reducing bioreactors improves performance through syntrophic H2 production.

bioRxiv · May 12, 2021 · PreprintMicrobiology