Author

G. Mastrobuoni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Bioengineering· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

S. Kempa· 5 shared E. Wyler· 2 shared M. Landthaler· 2 shared A. Boltengagen· 1 shared A. C. Hocke· 1 shared A. D. Gruber· 1 shared A. J. Rutkowski· 1 shared A. L'Hernault· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMicrobiology

S. Kempa

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

L-Glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and signaling

M. Forbes, R. Kempa, G. Mastrobuoni, L. Rayman, M. Pietzke, S. Bayram, B. Arlt, A. Spruessel, H. Deubzer, S. Kempa

This paper identifies a multi-modal mechanism by which L-GA inhibits neuroblastoma cell growth through metabolic disruption, oxidative stress, and nucleotide biosynthesis inhibition.

bioRxiv · Dec 20, 2023Biochemistry

Tissue protective role of Ganetespib in SARS-CoV-2-infected Syrian golden hamsters

L. G. Teixeira Alves, M. Baumgardt, J. Hoppe, T. C. Firsching, J. M. Adler, G. Mastrobuoni, J. Grobe, K. Hoenzke, S. Kempa, A. D. Gruber, A. C. Hocke, J. Trimpert, E. Wyler, M. Landthaler

This study shows that Ganetespib, an HSP90 inhibitor, reduces SARS-CoV-2 replication and inflammation in vitro and improves clinical outcomes in infected Syrian golden hamsters.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology

Spatio-temporal, optogenetic control of gene expression in organoids

I. Legnini, L. Emmenegger, A. Zappulo, R. Wurmus, A. Oliveras Martinez, C. Cerda Jara, A. Boltengagen, T. Hessler, G. Mastrobuoni, A. Rybak-Wolf, S. Kempa, R. P. Zinzen, A. Woehler, N. Rajewsky

This study uses optogenetic control to manipulate gene expression in organoids, demonstrating its ability to generate patterned tissue structures and reveal new insights into neurodevelopmental gene regulation.

bioRxiv · Sep 26, 2021 · PreprintBioengineering

Integrative functional genomics decodes herpes simplex virus 1

A. W. Whisnant, C. S. Juerges, T. Hennig, E. Wyler, B. Prusty, A. J. Rutkowski, A. L'Hernault, M. Goebel, K. Doering, J. Menegatti, R. Antrobus, N. J. Matheson, F. W. Kuenzig, G. Mastrobuoni, C. Bielow, , L. Doelken

This study decodes the complete HSV-1 transcriptome and translatome during lytic infection, identifying novel transcripts, ORFs, and regulatory elements.

bioRxiv · Apr 9, 2019Microbiology

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals

I. Iovinella, A. McAfee, G. Mastrobuoni, S. Kempa, L. J. Foster, P. Pelosi, F. R. Dani

This study identifies potential semiochemical carriers in Varroa destructor chemosensory organs through proteomic analysis.

bioRxiv · Feb 7, 2018Zoology