High-throughput laboratory evolution and evolutionary constraints in Escherichia coli
T. Maeda, J. Iwasawa, H. Kotani, N. Sakata, M. Kawada, T. Horinouchi, A. Sakai, K. Tanabe, C. Furusawa
This study uses high-throughput lab evolution of E. coli to identify evolutionary constraints and trade-offs in antibiotic resistance.
bioRxiv · Feb 19, 2020Evolutionary Biology