Author

T. Huo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein structure prediction· 2 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Z. Yu· 3 shared S. Ludtke· 2 shared W. Zheng· 2 shared X. Shi· 2 shared Y. Wu· 2 shared z. wangiD· 2 shared Z. Wang· 2 shared D. Nakada· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

Z. Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The assembly and efflux processes revealed by in situ structures of the ABC-type tripartite pump MacAB-TolC

T. Huo, W. Zheng, Z. Yu, Y. Wu, Q. Ren, J.-L. Cao, z. wang, X. Shi

The paper resolves the in situ structures of the MacAB-TolC efflux pump in E. coli, revealing its assembly process and substrate-driven efflux mechanism.

bioRxiv · Feb 22, 2024 · PreprintMicrobiology

In situ structures of secretins from bacterial type II secretion system reveal their membrane interactions and translocation process

Z. Yu, Y. Wu, M. Chen, T. Huo, W. Zheng, S. Ludtke, X. Shi, Z. Wang

The paper determines in situ structures of GspD and GspDβ secretins during translocation, revealing distinct membrane interaction patterns and translocation mechanisms.

bioRxiv · Jan 10, 2023 · PreprintMicrobiology

Full-length αIIbβ3 CryoEM structure reveals intact integrin initiate-activation intrinsic architecture

T. Huo, H. Wu, Z. Moussa, M. Sen, V. Dalton, Z. Wang

This paper presents the cryoEM structure of full-length αIIbβ3 integrin, revealing its activation states and providing insights into its role in platelet function and potential therapeutic targeting.

bioRxiv · Dec 19, 2022 · PreprintBiochemistry

Cryo-ET distinguishes platelets during pre-acute myeloid leukemia from steady state hematopoiesis

Y. Wang, T. Huo, Y.-J. Tseng, L. Dang, Z. Yu, W. Yu, Z. Foulks, S. Ludtke, D. Nakada, Z. Wang

The paper uses cryo-ET to identify structural changes in platelets during pre-acute myeloid leukemia, suggesting these changes could serve as an early diagnostic biomarker.

bioRxiv · Oct 18, 2021 · PreprintBiophysics