Author

S. Ludtke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

Z. Yu· 3 shared M. Chen· 2 shared T. Huo· 2 shared X. Shi· 2 shared Z. Wang· 2 shared B. Luisi· 1 shared D. Nakada· 1 shared G. Fan· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiophysics

Z. Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In situ structures of secretins from bacterial type II secretion system reveal their membrane interactions and translocation process

Z. Yu, Y. Wu, M. Chen, T. Huo, W. Zheng, S. Ludtke, X. Shi, Z. Wang

The paper determines in situ structures of GspD and GspDβ secretins during translocation, revealing distinct membrane interaction patterns and translocation mechanisms.

bioRxiv · Jan 10, 2023 · PreprintMicrobiology

Structural basis for tunable affinity and specificity of LxCxEdependentprotein interactions with the retinoblastoma protein family

S. Putta, L. Alvarez, S. Ludtke, P. Sehr, G. Muller, S. Fernandez, S. Tripathi, J. Lewis, T. Gibson, L. Chemes, S. Rubin

This study presents crystal structures of the p107 pocket domain bound to LxCxE peptides, revealing structural determinants that explain differences in binding affinity between viral and cellular proteins.

bioRxiv · Jun 10, 2022Biochemistry

Cryo-ET distinguishes platelets during pre-acute myeloid leukemia from steady state hematopoiesis

Y. Wang, T. Huo, Y.-J. Tseng, L. Dang, Z. Yu, W. Yu, Z. Foulks, S. Ludtke, D. Nakada, Z. Wang

The paper uses cryo-ET to identify structural changes in platelets during pre-acute myeloid leukemia, suggesting these changes could serve as an early diagnostic biomarker.

bioRxiv · Oct 18, 2021 · PreprintBiophysics

In situ structure of the AcrAB-TolC efflux pump at subnanometer resolution

M. Chen, X. Shi, Z. Yu, G. Fan, I. I. Serysheva, M. Baker, B. Luisi, S. Ludtke, Z. Wang

The paper uses cryo-ET to determine the 7 Å structure of the AcrAB-TolC efflux pump in Escherichia coli, revealing its activation mechanism through interprotein interactions.

bioRxiv · Jun 10, 2020Biophysics