Author

T. I. Doukov

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Wohlkonig· 1 shared C. J. Thomas· 1 shared C. Yates-Hansen· 1 shared G. G. Tall· 1 shared J. Johnston· 1 shared J. Steyaert· 1 shared K. Zhang· 1 shared L. J. McClelland· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Wohlkonig

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1 paper

Recent·Most cited

Crystal and cryo-EM structures of the cytosolic G protein alpha chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

L. J. McClelland, K. Zhang, T.-C. Mou, J. Johnston, C. Yates-Hansen, S. li, C. J. Thomas, T. I. Doukov, S. Triest, A. Wohlkonig, G. G. Tall, J. Steyaert, W. Chiu, S. R. Sprang

This study reports the crystal and cryo-EM structures of Ric-8A bound to Gαi1, revealing its mechanism of GTP exchange and chaperone activity through structural interactions.

bioRxiv · Jan 4, 2020 · PreprintBiochemistry