Regulation of multidrug efflux pumps by TetR family transcriptional repressor negatively affects secondary metabolism in Streptomyces coelicolor A3(2)
Y. Lei, S. Asamizu, T. Ishizuka, H. Onaka
This study identifies TFR-ABC transporter gene sets in Streptomyces coelicolor that regulate secondary metabolism and antibiotic resistance by repressing efflux pump expression.
bioRxiv · Nov 11, 2022 · PreprintMicrobiology