T. Fujiwara

StayGold Photostability under Different Illumination Modes

This study compares the photostability of StayGold with three other FPs under different illumination modes in microscopy, finding that StayGold maintains superior photostability in multi-beam LSCM but shows variable performance in single-beam LSCM.

Cure of congenital purpura fulminans via expression of engineered protein C through neonatal genome editing in mice

The paper demonstrates that ectopic expression of an engineered protein C via neonatal genome editing cures congenital protein C deficiency in mice.

SEN1 is responsible for molybdate transport into nodule symbiosomes for nitrogen fixation in Lotus japonicus

The paper identifies SEN1 as a molybdate transporter responsible for exporting molybdate from host plant cytosol to symbiosomes for nitrogen fixation in Lotus japonicus.

Transposons repressed by H3K27me3 were co-opted as cis-regulatory elements of H3K27me3 controlled protein coding genes during evolution of plants

The paper investigates how H3K27me3 marks transposons in different plant lineages and shows that these elements were co-opted as cis-regulatory elements for PRC2-controlled genes during evolution.

Energy transfer in ubiquitous rhodopsin pumps with xanthophyll antennas

The paper detects energy transfer from hydroxylated carotenoids to rhodopsin proton pumps in marine and freshwater bacteria.

A nano-liquid hub integrating growth and immune-evasion signaling to promote cell survival

The paper identifies GEM, a nano-liquid hub that integrates growth and immune-evasion signaling to enhance cell survival in mice.

Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami

The paper demonstrates that a simple system of dynein, microtubules, and DNA origami crosslinkers can produce oscillatory movement and repetitive bending without additional regulatory structures.

Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain

The paper maps biochemical propensities of conserved amino acids in the importin α IBB domain to understand its functional interactions and switching mechanisms across organisms.

Time-series Multi-spectral Imaging in Soybean for Improving Biomass and Genomic Prediction Accuracy

This study uses multi-spectral imaging to predict soybean biomass by analyzing growth stages and irrigation effects on genomic and phenotypic accuracy.

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

Liquid-liquid phase separation of florigen activation complex induces flowering

This study shows that the florigen activation complex (FAC) undergoes liquid-liquid phase separation, which is essential for flowering in plants.

Exploration of novel αβ-protein folds through de novo design

This study predicts and designs novel β-protein folds using topology rules, demonstrating their feasibility and suggesting a vast untapped space of possible folds.

Design of complicated all-α protein structures

This study designs complex all-α protein structures using helix-loop-helix motifs and canonical α-helices, achieving atomic accuracy and thermal stability in solution.

CASP microdomain formation requires cross cell wall stabilization of domains and non-cell autonomous action of LOTR1

The paper shows that LOTR1, an extracellular protease, is required for non-cell-autonomous positioning of Casparian Strip domains in plants, coordinating their formation across neighboring cells.

Pattern recognition receptors confer plant salt tolerance via WRKY18/WRKY40 transcription factors

This study identifies a mechanism by which pattern recognition receptors (PRRs) in Arabidopsis thaliana confer salt tolerance through WRKY18/WRKY40 transcription factors.

PIN FORMED 2 facilitates the transport of Arsenite in Arabidopsis thaliana

This study shows PIN2 facilitates arsenite transport in Arabidopsis, leading to arsenite accumulation and root growth inhibition.

OsNLP4 is required for nitrate assimilation gene expressions and nitrate-dependent growth in rice

The study identifies OsNLP4 as essential for nitrate assimilation gene expression and nitrate-dependent growth in rice.

Dynamic actin-mediated nano-scale clustering of CD44 regulates its meso-scale organization at the plasma membrane

This study reveals that CD44 forms a meso-scale meshwork at the plasma membrane, regulated by actin dynamics and nano-scale clustering.