Author

T. J. Kawecki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 6

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Organism:Drosophila· 6 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2

Frequent Co-Authors

B. Erkosar· 4 shared F. Cavigliasso· 3 shared H. Gallart-Ayala· 3 shared J. Ivanisevic· 3 shared L. Savary· 3 shared C. Dupuis· 2 shared M. Kapun· 2 shared A. Koval· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersEvolutionary Biology

B. Erkosar

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6 papers

Recent·Most cited

Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic adaptation to malnutrition in Drosophila

F. Cavigliasso, M. Savitskiy, A. Koval, B. Erkosar, L. Savary, H. Gallart-Ayala, J. Ivanisevic, V. L. Katanaev, T. J. Kawecki

This study identifies a cis-regulatory polymorphism in fiz that contributes to polygenic adaptation to malnutrition in Drosophila melanogaster by modulating ecdysone oxidase activity and larval growth.

bioRxiv · Aug 28, 2023 · PreprintEvolutionary Biology

Experimental evolution of metabolism under nutrient restriction: enhanced amino acid catabolism and a key role of branched-chain amino acids

F. Cavigliasso, L. Savary, J. Spangenberg, H. Gallart-Ayala, J. Ivanisevic, T. J. Kawecki

This paper shows that Drosophila melanogaster populations adapted to nutrient-poor diets evolved enhanced amino acid catabolism and a trade-off between amino acid use for energy and protein synthesis.

bioRxiv · Feb 6, 2023Evolutionary Biology

An Ancestral Balanced Inversion Polymorphism Confers Global Adaptation

M. Kapun, E. D. Mitchell, T. J. Kawecki, P. Schmidt, T. Flatt

This study investigates the population genomics of an inversion polymorphism in Drosophila melanogaster across four continents, finding evidence of balancing selection and climate-driven distribution patterns.

bioRxiv · Jan 31, 2023 · PreprintEvolutionary Biology

Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila

B. Erkosar, C. Dupuis, F. Cavigliasso, L. Savary, H. Gallart-Ayala, J. Ivanisevic, T. J. Kawecki

This study shows that evolutionary adaptation to juvenile malnutrition in Drosophila leads to metabolic changes in adults that impair fitness, suggesting non-independent evolution of juvenile and adult metabolism.

bioRxiv · Jan 11, 2022Evolutionary Biology

The genomic architecture of adaptation to larval malnutrition points to a trade-off with adult starvation resistance in Drosophila

T. J. Kawecki, B. Erkosar, C. Dupuis, B. Hollis, R. C. Stillwell, M. Kapun

This study identifies genomic regions associated with adaptation to larval malnutrition in Drosophila and finds a trade-off with adult starvation resistance.

bioRxiv · Dec 1, 2020Evolutionary Biology

Adaptation to chronic malnutrition leads to reduced dependence on microbiota in Drosophila

B. Erkosar, S. Kolly, J. R. van der Meer, T. J. Kawecki

This study shows that Drosophila populations adapted to chronic malnutrition rely less on microbiota for digestion and growth, with changes in dFOXO targets.

bioRxiv · Mar 6, 2017Evolutionary Biology