Author

T. K. Chua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. R. Crane· 1 shared C. Jie· 1 shared C. Y. Chong· 1 shared C. Y. P. Lee· 1 shared F. Ginhoux· 1 shared F. M. Lum· 1 shared J. Chan· 1 shared J. Hiscox· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

B. R. Crane

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2 papers

Recent·Most cited

Interdomain linkers regulate histidine kinase activity by controlling subunit interactions

Z. Maschmann, S. Chandrasekaran, T. K. Chua, B. R. Crane

This study shows that interdomain linkers in CheA regulate kinase activity by modulating subunit interactions and domain dynamics.

bioRxiv · Aug 17, 2021Biophysics

Trimester-specific Zika virus infection affects placental responses in women

F. M. Lum, V. Narang, S. Hue, C. Jie, N. McGovern, R. Rajarethinam, J. Tan, S. N. Amrun, Y. H. Chan, C. Y. P. Lee, T. K. Chua, W. X. Yee, N. K. W. Yeo, T. C. Tan, L. Xuan, , L. Ng

This study examines how ZIKV infection during different pregnancy trimesters affects placental immune and transcriptomic responses, identifying unique molecular changes associated with early infection.

bioRxiv · Aug 6, 2019 · PreprintImmunology