Author

B. R. Crane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 4 Assay:proteomics· 4 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1

Frequent Co-Authors

S. Chandrasekaran· 3 shared A. BriegeliD· 2 shared C. Li· 2 shared S. Zhang· 2 shared W. Yang· 2 shared Z. Maschmann· 2 shared A. Bah· 1 shared A. Ganguly· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

S. Chandrasekaran

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Lysinoalanine crosslinking is a conserved post-translational modification in the spirochete flagellar hook

M. J. Lynch, M. Deshpande, K. Kyrniyati, K. Zhang, M. James, M. Miller, S. Zhang, F. J. Passalia, E. A. Wunder, N. W. Charon, C. Li, B. R. Crane

The paper identifies lysinoalanine (Lal) crosslinks in spirochete flagellar hooks across multiple species, showing they are conserved and necessary for motility.

bioRxiv · Jun 13, 2023Microbiology

Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock

D. Tariq, N. Maurici, B. Bartholomai, S. Chandrasekaran, J. C. Dunlap, A. Bah, B. R. CRANE

This study investigates how phosphorylation, disorder, and phase separation regulate the behavior of Frequency (FRQ) in the fungal circadian clock of Neurospora crassa.

bioRxiv · Nov 3, 2022Biochemistry

Mechanistic insight into light-dependent recognition of Timeless by Drosophila cryptochrome

C. Lin, C. M. Schneps, S. Chandrasekaran, A. Ganguly, B. R. Crane

The paper investigates how light affects CRY-TIM binding in Drosophila using a new assay and shows that flavin redox state and histidine residues control this interaction.

bioRxiv · Sep 10, 2021Biochemistry

Interdomain linkers regulate histidine kinase activity by controlling subunit interactions

Z. Maschmann, S. Chandrasekaran, T. K. Chua, B. R. Crane

This study shows that interdomain linkers in CheA regulate kinase activity by modulating subunit interactions and domain dynamics.

bioRxiv · Aug 17, 2021Biophysics

Atypical chemoreceptor arrays accommodate high membrane curvature

A. R. Muok, D. R. Ortega, K. Kurniyati, W. Yang, A. Sidi Mabrouk, C. Li, B. R. Crane, A. Briegel

This study identifies an alternative P2 symmetry in chemoreceptor arrays of Treponema denticola, adapted to high membrane curvature, revealing new structural features and functional roles of CheA and CheW-CheR-like proteins.

Nature Communications · Nov 13, 2020Peer-reviewedMicrobiology

Engineered chemotaxis core signaling units indicate a constrained kinase-off state

A. Muok, T. Khiang Chua, M. Srivastava, W. Yang, Z. Maschmann, P. P. Borbat, J. Chong, S. Zhang, J. H. Freed, A. Briegel, B. R. Crane

The paper investigates how engineered chemoreceptor complexes stabilize a kinase-off state by sequestering kinase and substrate domains, using multiple biophysical techniques.

Science Signaling · Nov 10, 2020Peer-reviewedBiochemistry