Author

T. K. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Q. Lin· 2 shared C. Y. He· 1 shared E. J. Rubin· 1 shared G. Grueber· 1 shared J. Sarathy· 1 shared J. Shin· 1 shared J. Zhu· 1 shared M. Gengenbacher· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Q. Lin

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2 papers

Recent·Most cited

Flagellar targeting of an arginine kinase requires the conserved Lipidated Intraflagellar Transport (LIFT) pathway in Trypanosoma brucei

M. Pandey, Y. Huang, T. K. Lim, Q. Lin, C. Y. He

This study identifies TbUnc119 as a myristoylated cargo carrier in Trypanosoma brucei, showing its role in targeting the arginine kinase TbAK3 to the flagellum via the conserved LIFT pathway.

bioRxiv · May 7, 2020Cell Biology

Pyrazinamide triggers degradation of its target aspartate decarboxylase

P. Gopal, J. Sarathy, M. Yee, P. Ragunathan, J. Shin, S. Bhushan, J. Zhu, T. Akopian, O. Kandror, T. K. Lim, M. Gengenbacher, Q. Lin, E. J. Rubin, G. Grueber, T. Dick

This paper shows that pyrazinamide's active form, POA, triggers degradation of its target enzyme PanD via the ClpC1-ClpP protease, rather than inhibiting it directly.

Nature Communications · Apr 3, 2020Peer-reviewedMicrobiology