T. K. Nielsen

The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin resistant Staphylococcus aureus

This study identifies Spx as a stress regulator that enhances β-lactam resistance and reduces susceptibility to last-line antibiotics in MRSA through a redox-independent mechanism.

Activity and diversity of prophages harbored by wheat phyllosphere bacteria

The paper identifies and quantifies active prophages in wheat-associated bacteria using VIP-Seq, showing their role in bacterial competition and potential impact on microbiome function.

Metaviromes reveal the dynamics of Pseudomonas host-specific phages cultured and uncultured by plaque assay

The paper uses metaviromes to study Pseudomonas host-specific phages, showing shifts in phage communities and highlighting the value of long-read sequencing for metavirome assembly.

Analyses of the complete genome sequence of 2,6-dichlorobenzamide (BAM) degrader Aminobacter sp. MSH1 suggests a polyploid chromosome, phylogenetic reassignment, and functions of (un)stable plasmids.

The paper presents the complete genome of Aminobacter sp. MSH1, revealing a polyploid chromosome, phylogenetic reassignment, and varying plasmid content between substrains.

Mobilization of antibiotic resistance genes differ by resistance mechanism

The paper assesses how antibiotic resistance genes (ARGs) are mobilized by genetic elements and finds that some ARGs are more likely to confer resistance through overexpression than others.

Potential Rhodopsin and Bacteriochlorophyll-Based Dual Phototrophy in a High Arctic Glacier

The paper identifies four glacier bacteria capable of dual phototrophy using bacteriochlorophyll and rhodopsin, showing genomic evidence of horizontal gene transfer for these systems.