R. Lavigne

The branched receptor binding complex of Ackermannviridae phages promotes adaptative host recognition

This study shows Ackermannviridae phages can acquire new tail spike proteins to expand their branched receptor complex, enabling adaptation to new hosts.

Understanding the bacterial imbalance in Hidradenitis Suppurativa patients: Insights into microbial community shifts and colonization by opportunistic pathogens

This study analyzes the microbial community shifts in HS lesions compared to healthy skin, identifying bacterial imbalances and opportunistic pathogens associated with disease progression.

Hidradenitis suppurativa patients exhibit a distinctive and highly individualized skin virome

This study identifies distinct viral communities in HS patients compared to controls, highlighting differences in phage composition and potential roles in disease progression.

Refining the transcriptional landscapes for distinct clades of virulent phages infecting Pseudomonas aeruginosa

This study uses ONT-cappable-seq to map transcriptional landscapes of six Pseudomonas aeruginosa phages, revealing new regulatory elements and gene expression mechanisms.

Evolutionarily conserved ovarian fluid proteins are responsible for extending egg viability in salmonid fish

The paper identifies salmonid-specific proteins in ovarian fluid that enhance egg viability by analyzing proteomic differences and testing biological activity.

Rapid assessment of changes in phage bioactivity using dynamic light scattering

This paper uses Dynamic Light Scattering to assess phage bioactivity changes over time and optimize storage conditions for clinical phage applications.

Immediate targeting of host ribosomes by jumbo phage encoded proteins

This study identifies phage-encoded proteins that target host ribosomes to modulate translation in Pseudomonas aeruginosa.

The paradoxical relationship between CRISPR-Cas and phage susceptibility in Pseudomonas aeruginosa

This study examines the genomic and phenotypic effects of CRISPR-Cas systems in Pseudomonas aeruginosa, revealing a paradoxical link between CRISPR presence and increased phage susceptibility.

Transcriptomics-driven characterisation of novel T7-like temperate Pseudomonas phage LUZ100

This paper characterizes Pseudomonas phage LUZ100 using transcriptomics, revealing temperate behavior and regulatory elements that challenge the notion of T7-like phages being strictly lytic.

Unraveling protein interactions between the temperate virus Bam35 and its Bacillus host using an integrative yeast two hybrid-high throughput sequencing approach

This paper identifies 183 high-confidence protein-protein interactions between the temperate virus Bam35 and its Bacillus thuringiensis host using a yeast two-hybrid combined with high-throughput sequencing approach.

Analyses of the complete genome sequence of 2,6-dichlorobenzamide (BAM) degrader Aminobacter sp. MSH1 suggests a polyploid chromosome, phylogenetic reassignment, and functions of (un)stable plasmids.

The paper presents the complete genome of Aminobacter sp. MSH1, revealing a polyploid chromosome, phylogenetic reassignment, and varying plasmid content between substrains.

The fully resolved genome of Bacillus thuringiensis HER1410 reveals a cry-containing chromosome, two megaplasmids & an integrative plasmidial prophage

This paper presents the fully resolved genome of Bacillus thuringiensis HER1410, identifying three plasmids, including two megaplasmids and an integrative prophage, and revealing an unusual cry gene location.

Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB

The paper shows that phosphorylation of SHARPIN at serine 165 is required for optimal NF-κB activation, despite not affecting linear ubiquitin chain formation.

Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavor and texture in blue cheeses

This study shows that P. roqueforti strains from different populations affect blue cheese characteristics like blue color, volatile compounds, and water activity, with Roquefort strains producing more aromatic compounds and lower water availability.

Pseudomonas aeruginosa PA5oct jumbo phage impacts planktonic and biofilm population and reduces its host virulence

This paper investigates the impact of jumbo phage PA5oct on P. aeruginosa populations and virulence, finding that it reduces bacterial numbers and virulence while persisting in resistant clones.

Megaplasmids on the rise: combining sequencing approaches to fully resolve a carbapenemase-encoding plasmid in a proposed novel Pseudomonas species

The paper combines Nanopore and Illumina sequencing to fully assemble a carbapenemase-encoding megaplasmid from a putative novel Pseudomonas species.

Host metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation

This study shows that phage LUZ19 modulates Pseudomonas aeruginosa quorum sensing by expressing Qst, which interacts with PqsD to reduce PQS metabolites, enabling successful infection.

Protection of phage applications in crop production: a patent landscape.

This study analyzes scientific publications and patents to assess R&D focus on phage biocontrol in agriculture, finding growing activity and broad patent claims.

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

This study investigates the origin, evolution, and epidemiology of crAssphage, a widespread human gut virus, using global DNA sequences showing local phylogeographic clustering and ancient primate associations.

Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Bacteriophages

The paper evaluates taxonomy methods for bacteriophages using Spounavirinae as a case study, finding they should be divided into at least five subfamilies.

Numerous cultivated and uncultivated viruses encode ribosomal proteins

The paper identifies ribosomal proteins encoded by viruses across diverse genomes and metagenomes, challenging the assumption that viruses lack these core translation components.