T. Kraft

Sorafenib induces muscle wasting by disrupting the activity of distinct chromatin regulators

This study shows Sorafenib causes muscle wasting by disrupting chromatin regulators, leading to transcriptional changes and impaired muscle function.

Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemo-mechanical properties despite the same myosin heavy chain isoform.

This study compares the chemo-mechanical properties of cardiac ventricular and slow skeletal myosins with the same heavy chain isoform, finding distinct kinetic and mechanical behaviors.

Myosin essential light chain 1sa decelerates actin and thin filament gliding on β-myosin molecules

The paper shows that MLC1sa in soleus myosin slows actin gliding compared to MLC1sb/v in ventricular myosin, likely due to increased actin affinity and reduced dissociation rate.

APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population

The paper examines the association between APOE4 and blood lipid levels and innate immune biomarkers in Tsimane forager-farmers, finding lower inflammation and higher cholesterol levels linked to APOE4.

The Life History of Human Foraging: Cross-Cultural and Individual Variation

The paper analyzes hunting skill data from 1,800 individuals to infer age-related productivity patterns and variation in human foraging.